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parabricks

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Description

NVIDIA's Clara Parabricks brings next generation sequencing to GPUs, accelerating an array of gold-standard tooling such as BWA-MEM, GATK4, Google's DeepVariant, and many more. Users can achieve a 30-60x acceleration and 99.99% accuracy for variant calling when comparing against CPU-only BWA-GATK4 pipelines, meaning a single server can process up to 60 whole genomes per day. These tools can be easily integrated into current pipelines with drop-in replacement commands to quickly bring speed and data-center scale to a range of applications including germline, somatic and RNA workflows.

NGC Catalog

https://catalog.ngc.nvidia.com/orgs/nvidia/teams/clara/containers/clara-parabricks

Available Versions on RCAC Clusters

Cluster Versions
ANVIL 4.0.0-1
GILBRETH 4.0.0-1, 4.4.0-1
SCHOLAR 4.0.0-1

Module

You can load the container module by:

module load ngc
module load parabricks

Note for using parabricks

Run module spider parabricks beforehand to check available versions and any prerequisite modules.